This domain represents a conserved region in pyruvate carboxylase (PYC) (<db_xref db="EC" dbkey="6.4.1.1"/>), oxaloacetate decarboxylase alpha chain (OADA) (<db_xref db="EC" dbkey="4.1.1.3"/>), and transcarboxylase 5s subunit (<db_xref db="EC" dbkey="2.1.3.1"/>). The domain is found adjacent to the HMGL-like domain (<db_xref db="INTERPRO" dbkey="IPR000891"/>) and often close to the biotin_lipoyl domain (<db_xref db="INTERPRO" dbkey="IPR000089"/>) of biotin requiring enzymes. Carboxylase, conserved domain